沙丁胺醇联合布地奈德治疗支气管哮喘急性发作51例临床观察

Albuterol Joint Budesonide Treating Bronchial Asthma With Acute Onset of 51 Cases of Clinical Observation

目的观察临床应用沙丁胺醇联合布地奈德治疗小儿支气管哮喘急性发作治疗效果。方法选择支气管哮喘急性发作的小儿患者102例,将所有患儿随机分为观察组与对照组,各51例。对照组患儿在常规治疗的基础上单纯采用沙丁胺醇雾化吸入治疗,观察组患儿采用沙丁胺醇联合布地奈德雾化吸入治疗,观察两组的治疗效果。结果观察组的总有效率为96.08%,优于对照组的总有效率80.39%,由此可见此差异具有统计学意义(P<0.05);不良反应发生率为5.8%,低于对照组9.8%,差异具有统计学意义(P>0.05)。结论采用沙丁胺醇、布地奈德联合治疗支气管哮喘急性发作,具有较好的治疗效果,值得在临床上进一步推广应用。

Objective To observe the clinical application of salbutamol joint budesonide treating infantile bronchial asthma acute therapeutic effect. Methods Choose 102 patients with acute bronchial asthma in children,all the children were randomly divided into observation group and control group, 51 cases each. Children with the control group on the basis of conventional treatment only with salbutamol aerosol inhalation therapy, observation group with the joint budesonide atomization inhalation salbutamol treatment,observe the therapeutic effect of two groups. Results The total effective rate was 96. 0 8 % , the observation group is better than the control group total effective rate 80. 3 9 % , this shows the difference statistically significant （P 〈0. 05） ; The incidence of adverse reactions was 5. 8%,9. 8% lower than the control group, difference has statistical significance （ P 〉 0.05）. Conclusion Using salbutamol,combination treatment with budesonide acute bronchial asthma, has good treatment effect, worthy of further popularization and application in clinic.