显微手术治疗脑干及围脑干肿瘤80例临床观察

Clinical analysis of microsurgical treatment of brainstem and brainstem tumors

目的:探讨显微手术切除脑干及围脑干肿瘤的方法及临床疗效。方法:将130例脑干及围脑干肿瘤患者按治疗方式不同分为两组:手术组80例行显微手术治疗,对照组50例采用放化疗。比较两组临床疗效。结果:手术组总有效率为87.50%,高于对照组的62%,差异有统计学意义(P<0.05)。结论:显微神经外科手术能有效治疗脑干及围脑干肿瘤,但要正确选择手术适应证和手术入路,规范化操作。

Objective： To investigate the method and clinical effect of microsurgery for resection of brain stem and brainstem tumors. Methods： 130 patients with brain stem and brainstem tumors were divided into two groups according to different treatment methods： the operation group （n = 80） was treated by microsurgery, and the control group （n=50） was treated with radiotherapy and chemotherapy. The clinical efficacy of the two groups was com-pared. Results： The total effective rate of the operation group was 87. 50% higher than that of the control group, and the difference was statistically significant （P〈0.05） （62%）. Conclusion： The operation of microsurgery in the department of neurosurgery can effectively treat the brain stem and the brain stem tumor, but it is necessary to choose the surgical indications and the surgical approach correctly.