单硝酸异山梨酯联合阿司匹林治疗心绞痛的疗效及预后影响

Curative effect and prognosis influence of isosorbide mononitrate combined with aspirin in the treatment of patients with angina pectoris

目的研究单硝酸异山梨酯联合阿司匹林肠溶片对心绞痛患者的疗效及预后效果。方法选取2014年4月~2016年3月在我院接受治疗的94例心绞痛患者,以随机数字表法均分为观察组与对照组。所有患者均给予单硝酸异山梨酯,观察组在此基础上加用阿司匹林肠溶片,对比2组的疗效及预后效果。结果观察组治疗总有效率显著高于对照组;治疗前2组心绞痛发作频率及持续时间差异均无统计学意义。观察组心绞痛发作频率及持续时间均显著低于对照组;观察组住院次数、治疗费用及治疗后心脏事件发生率和死亡率均显著低于对照组(P<0.05)。结论单硝酸异山梨酯联合阿司匹林肠溶片治疗心绞痛效果显著,且预后效果较好。

Objective To study the curative effect and prognosis influence of isosorbide mononitrate combined with Aspirin Entericcoated Tablets in patients with angina pectoris.Methods 94 cases with angina pectoris from April 2014 to March 2016 in our hospital were randomly divided into the observation group and the control group.All patients were given isosorbide mononitrate,but the observation group were given addtionally Aspirin Enteric-coated Tablets.The curative effects and prognosis were compared between the 2groups.Results Total efficiency of the observation group was significantly higher than that of the control group;before treatment,the angina attack frequency and duration of the 2groups were not significantly different,while after treatment the observation group′s angina attack frequency and duration were significantly lower than that of the control group.After the treatment,the times of hospitalization,the incidence of cardiac events and the mortality rates of the observation group were significantly lower than that of the control group（P〈0.05）.Conclusion Isosorbide mononitrate combined with Aspirin Enteric-coated Tablets in the treatment of angina pectoris is effective,and the prognosis is satisfactory.