广西贵港市艾滋病/肺结核双重感染病例生存时间及影响因素分析

Analysis of factors in Guangxi Guigang City of HIV/TB patient survival time and influence

目的了解贵港市艾滋病/肺结核双重感染病例的生存时间分布特征及其影响因素。方法采用回顾性研究,收集截至2013年12月31日艾滋病综合防治数据信息系统中现住址为本地艾滋病/肺结核双重感染病例为研究对象,采用Cox风险回归模型分析其生存时间的影响因素。结果 400例双重感染病例累计死亡172例,2008-2013年分别死亡12例、22例、26例、32例、49例、31例,临床诊断为艾滋病相关疾病死亡的占74.42%(128/172),病死率为32.00%(128/400)。平均死亡年龄为(51.64±15.93)岁,研究对象的HIV确认后存活时间均数为1.56年。单因素分析结果显示:发现传播途径、年龄对生存时间影响有显著性意义。结论艾滋病/肺结核双重感染病例监测工作滞后,病死率较高,应进一步加大农村宣传教育力度,促进人们及早参加检测和主动参与治疗。

Objective To analyze characteristics of survival time and influencing factors among HIV/TB infected patients in Guigang City. Methods The retrospective study was used, AIDS prevention and control information system by the end of December 31, 2013, according to all the current address for the local HIV/TB infected persons and patients as the research object, collect the death report relevant information, using Cox proportional hazard regression model to analyze the factors of HIV infec- ted persons and patients survival time. Results Among the 400 death cases, 12, 22, 26, 32, 49 and 31 died in 2008, 2009, 2010, 2011, 2012 and 2013 respectively. Among the 172 death cases, the clinical diagnosis of AIDS related disease deaths accounted for 74.42% （ 128/172）, the case fatality rate was 32.00% （128/400）. The average death age was（51.64 ± 15.93 ）. The median survival time of all the death cases was 1.56 years. Single factor analysis showed that there was a significant difference in the effect of transmission route and age on the survival time. Conclusion The monitoring work is lag and the fatality rate is high, so we should further intensify propaganda and education in rural areas, promote people to participate in the detection and active participation in treatment.