桂枝茯苓胶囊对卵巢囊肿患者囊肿核摘除术后血清雌激素、AMH及LSA水平的影响

Effects of Guizhi Fuling Capsule on the Serum Estrogen, AMH and LSA Levels of Patients with Ovarian Cyst after Laparoscopic Excision

目的:探究桂枝茯苓胶囊对卵巢囊肿患者囊肿核摘除术后血清雌激素、抗苗勒氏管激素(AMH)及脂质结合唾液酸(LSA)水平的影响。方法:选择我院收治的已行囊肿核摘除术的卵巢囊肿患者39例,将其随机分为实验组及对照组。对照组18例予甲硝唑联合青霉素注射治疗;实验组21例予桂枝茯苓胶囊治疗。治疗后,对比两组的临床疗效及治疗前后血清雌激素、AMH及LSA的水平。结果:治疗后,实验组总有效率(95.2%)显著高于对照组(72.2%),差异具有统计学意义(P<0.05);治疗后,两组血清雌激素、AMH水平均明显升高,血清LSA水平显著降低,差异均具有统计学意义(P<0.05);与对照组比较,实验组治疗后血清雌激素、AMH较高,而LSA水平较低,差异具有统计学意义(P<0.05)。结论:桂枝茯苓胶囊可以有效提高行囊肿核摘除术卵巢囊肿患者的临床疗效,这可能与其提高血清雌激素及AMH水平并降低血清LSA水平有关。

Objective：To investigate the effects of Guizhi ruling capsule on the serum levels of estrogen,AMH and LSA in patients with ovarian cyst after surgical removed the cyst nucleus.Methods：39 patients with ovarian cyst after surgical removed the cyst nucleus who were treated in our hospital were selected and randomly divided into experiment group and control group.18 cases in the control group were treated with metronidazole combined with penicillin,and another 21 cases in the experiment group were treated with Guizhi ruling capsule.Then the clinical efficacy and the serum levels of estrogen,anti miao le＇s tube hormone （AMH） and lipid sialic acid （LSA） in the two groups were observed and compared before and after the treatment.Results：The total effective rate of the experiment group was 95.2%,which was higher than 72.2% in the control group,and the difference was statistically significant （P〈0.05）;After treatment,the serum levels of estrogen and anti miao le＇s tube hormone （AMH） increased in the two groups,while the levels of serum lipid sialic acid （LSA） decreased,and the differences were statistically significant （P〈0.05）;Compared with the control group,the levels of estrogen and AMH of the experiment group were higher,and the LSA level was lower,and the differences were statistically significant （P〈0.05）.Conclusion：Guizhi fuling capsule can effectively relieve symptoms,strengthen the function of ovarian reserve,which may be relate to the increase of the estrogen and AMH,and the decrease of the LSA.