阿奇霉素联合甲泼尼龙治疗肺炎支原体肺炎患儿的临床疗效及安全性分析

The analysis of clinical efficacy and safety of azithromycin combined with methylprednisolone treatment in children with mycoplasma pneumonia

目的观察阿奇霉素联合甲泼尼龙治疗肺炎支原体肺炎患儿的临床疗效及安全性。方法将肺炎支原体肺炎患儿210例按入院单双号顺序分为研究组和对照组各105例,研究组给予阿奇霉素联合甲泼尼龙治疗,对照组给予阿奇霉素治疗。比较2组临床疗效、不良反应发生状况。结果研究组患儿的治疗总有效率为94.29%高于对照组的80.95%,差异有统计学意义(P<0.05)。研究组患儿住院时间、咳嗽消失时间、退热时间均短于对照组,差异有统计学意义(P<0.05)。结论采用阿奇霉素联合甲泼尼龙治疗肺炎支原体肺炎患儿,其疗效显著,可有效缓解患儿临床症状,不良反应少,安全性高,具有临床应用及推广价值。

Objective To observe the clinical efficacy and safety of azithromycin combined with methylprednisolone treatment in children with mycoplasma pneumonia.Methods 210 patients admitted to hospital with single and double sequence was divided into two groups,105 cases in the control group.The study group was treated with azithromycin combined with methylprednisolone,and the control group was treated with azithromycin.The clinical curative effect and the adverse reaction between the two groups were compared.Results The total effective rate of study group（94.29%） was higher than that of control group（80.95%）,the difference was statistically significant（P〈0.05）.The hospitalization time,cough disappearance time,fever time of the study group were shorter than those of the control group,the differences were statistically significant（P〈0.05）.Conclusion Azithromycin combined with methylprednisolone treatment in children with mycoplasma pneumonia,it is curative effect,can effectively relieve clinical symptoms,less adverse reaction,high safety,and it has clinical application and popularization value.