3C整合系统与双C系统强化降糖在2型糖尿病患者中的疗效与安全性比较

Comparison of efficacy and safety of “3C” Integrated System and Double C System in intensive hypoglycemic therapy of patients with type 2 diabetes mellitus

目的比较3C整合系统(美敦力722胰岛素泵)和双C系统(美敦力712胰岛素泵)治疗2型糖尿病高血糖患者疗效与安全性。方法 2015年1—12月住院的60例2型糖尿病高血糖患者,分别给予3C整合系统(美敦力722胰岛素泵)和双C系统(美敦力712胰岛素泵)治疗,根据血糖监测及并病情变化情况,调整胰岛素泵用量,记录相应指标。结果 1、第2、3日内血糖水平差异有统计学意义(P<0.05),3C整合系统(美敦力722胰岛素泵)的降糖效果明显双C系统(美敦力712胰岛素泵);2、两组治疗后血糖漂移有明显差异(P<0.05),3C整合系统(美敦力722胰岛素泵)治疗血糖控制更平稳。3;两组治疗后第3日早餐前血糖、午餐前血糖、睡前血糖、夜3点血糖比较差异有统计血糖意义(P<0.05);4、治疗后低血糖发生率有明显差异(P<0.05),说明3C整合系统(美敦力722胰岛素泵)治疗低血糖发生率更低。结论 3C整合系统(美敦力722胰岛素泵)能够更快、更平稳、更安全的控制血糖。

Objective To compare the efficacy and safety of ＂3C＂ Integrated System （Medtronic 722 insulin pump） and ＂Double C＂ System （Medtronie 717 insuhn pump） in treating the patients with type 2 diabetes mellitus. Methods 60 patients with type 2 diabetes meUitus who were hospitalized in our hospital from January to December in 2015 were divided into two groups and were given treatment of ＂3C＂ Integrated System （Medtronic 722 insuhn pump） and ＂Double C＂ System （Medtronic 717 insulin pump ）. According to the changes of blood glucose , we adjusted the dosage of insulin pump and recorded the corresponding indicators. Results There was a statistically significant difference about blood glucose levels within 2nd, 3rd days （P〈0.05） ,3C integrated systems （insulin pumps Medtronie 722） had obvious glucose-lowering curative effect compared with Double-C system （Medtronic insulin pump 712）. o Blood glucose in two groups had significant changes after they were treated （P〈O.05）, and the 3C integrated system （Medtronic insulin pump 712 ） was more stable. The statistic data of the 3rd day blood glucose： including data before breakfast, before lunch, before bed, 3 o＇elack at night between two groups had statistical differences （P〈O.05）. The incidence of hypoglycemia also had significant difference after treatment （P〈O.05）. 3C integrated systems （insulin pumps Medtronie 722） had lower rate of hypoglycemia. Conclusion ＂3C＂ Integrated System （Medtronic 722 insulin pump） can control blood glucose, more stably, more securely and faster.