中药灌肠联合黄芪注射液穴位注射治疗盆腔瘀血综合征临床观察

Clinical Observation of Herbal Enema Combined with Point Injection of Astragalus Injection for Pelvic Congestion Syndrome

目的:观察在口服血府逐瘀丸的基础上加中药灌肠联合黄芪注射液穴位注射治疗盆腔瘀血综合征的临床疗效。方法:将86例盆腔瘀血综合征患者纳入研究,随机分为对照组42例和观察组44例。对照组口服血府逐瘀丸,观察组在对照组用药基础上加中药灌肠合黄芪注射液穴位注射,2组均治疗1月。观察2组治疗前后证候积分、血液流变学指标及盆腔静脉暗带内径的变化,比较2组临床疗效。结果:治疗后,2组证候积分及纤维蛋白原(Fib)、血浆黏度、全血黏度低切、全血黏度高切水平均较治疗前降低(P<0.05);观察组的证候积分及4项血液流变学指标水平均下降更明显(P<0.05)。治疗后,2组盆腔静脉暗带内径均较治疗前缩短(P<0.05);观察组的盆腔静脉暗带内径短于对照组(P<0.05)。对照组总有效率78.57%,观察组总有效率95.45%,2组比较,差异有统计学意义(P<0.05)。结论:在使用血府逐瘀丸的基础上加中药灌肠合黄芪注射液穴位注射治疗盆腔瘀血综合征,能更有效地改善患者的症状、血液流变学指标及盆腔静脉暗带内径。

Objective：To observe the clinical effect of herbal enema combined with point injection of astragalus injection based on Xuefu Zhuyu pills for pelvic congestion syndrome. Methods：86 cases of patients with pelvic congestion syndrome were brought into the study and were divided into the control group and the observation group randomly,42 cases in control group and 44 cases in observation group. Both groups received Xuefu Zhuyu pills orally,while the observation group additionally received herbal enema combined with point injection of astragalus injection. Both groups received treatment for one month.Observed syndrome scores and changes of hemorheology indexes as well as the inner diameter of pelvic vein in both groups before and after treatment. Compared the clinical effect in the two groups. Results：After treatment,symptom scores and levels of fibrinogen（Fib）,whole blood viscosity in low shear rate,whole blood viscosity in high shear rate and plasma viscosity in two groups were decreased when compared with those before treatment（P〈0.05）. The decreases of symptom scores and changes of four hemorheology indexes were more obvious in the observation group（P〈0.05）. The inner diameters of pelvic vein in both groups after treatment were shortened,comparing with those before treatment（P〈0.05）,and the inner diameter of pelvic vein in the observation group was shorter than that in the control group（P〈0.05）. The total effective rate was 78.57% in the control group and 95.45% in the observation group,the difference being significant（P〈0.05）. Conclusion：The therapy of herbal enema combined with point injection of astragalus injection based on Xuefu Zhuyu pills for pelvic congestion syndrome can more effectively improve symptoms and hemorheology indexes of the patients.