视黄醇结合蛋白4的生物学作用研究进展

Research Progress on Biological Effect of Retinol-binding Protein 4

视黄醇结合蛋白(Retinol-binding protein,RBP)是一类疏水性运载蛋白,其中的视黄醇结合蛋白4(RBP4)是目前已经证实的唯一一类可在血液中转运视黄醇的蛋白。RBP4在机体的各个脏器中均有表达,肝脏为主要表达场所,视黄醇在家禽繁殖过程中起到一定的促进作用,而RBP4参与视黄醇的存储、代谢和吸收过程。文章针对RBP4对家禽繁殖性能影响方面的研究进展进行论述,以初步揭示该蛋白与家禽繁殖性能之间的关系。

Retinol binding protein （RBP） is a kind of hydrophobic carrier protein. The retinol binding protein 4 （RBP4） is currently the only confirmed a class of transport of retinol in blood protein. RBP4 is expressed in various organs of the body. The liver is the main site of expression,vitamin A plays a role in the promotion of poultry breeding, and RBP4 is involved in the storage, metabolism and absorption of vitamin A. In this paper, the effects of RBP4 on reproductive performance of poultry was discussed and the relationship between the protein and reproductive performance was revealed.