前列地尔、依帕司他联合复方三维B治疗糖尿病周围神经病变的作用

Effects of Alprostadil and Epalrestat Combined With Compound Three Dimensional B on Diabetic Peripheral Neuropathy

目的分析前列地尔、依帕司他联合复方三维B治疗糖尿病周围神经病变的有效性。方法选择2014年8月—2016年8月我院收治的90例糖尿病周围神经病变患者为分析对象,分为两组,对照组(n=45)选用安慰剂进行治疗,观察组(n=45)采用前列地尔、依帕司他联合复方三维B进行治疗,观察两组患者的治疗效果。结果观察组患者的总有效率为95.56%,对照组的总有效率为77.78%,观察组高于对照组(P<0.05);在治疗中,两组均出现少数头晕、局部疼痛等不良反应,对症治疗后不良反应均消失(P>0.05)。结论在对糖尿病周围神经病变患者进行治疗时,采用依帕司他与前列地尔联合复方三维B实施治疗,能够有效提高患者的临床治疗效果,帮助患者早日康复。

Objective To evaluate the efficacy of alprostadil and epalrestat in combination with 3D-B in the treatment of diabetic peripheral neuropathy. Methods Ninety patients with diabetic peripheral neuropathy treated in our hospital from August 2014 to August 2016 were divided into two groups. The control group （n = 45） was treated with placebo, and the observation group （n = 45） were treated with alprostadil, epalrestat and combination of three-dimensional B to observe the treatment of patients in the two groups. Results The total effective rate of the observation group was 95.56%, the total effective rate of the control group was 77.78%, the observation group was significantly higher than the control group （P 〈0.05）; in the treatment of both groups a small number of dizziness, local pain Adverse reactions, symptomatic treatment of adverse reaetions disappeared （P〉 0.05）. Conclusion In the treatment of patients with diabetic peripheral neuropathy, the combination of epalrestat and alprostadil eombined with three-dimensional B can improve the clinical therapeutic effect and help the patients recover quickly, which is worthy of clinical application.