抗病毒药物联合小剂量强的松治疗亚急性甲状腺炎临床分析

Clinical Analysis of Antiviral Drugs Combined With Low-dose Prednisone in the Treatment of Subacute Thyroiditis

目的对抗病毒药物联合小剂量强的松治疗亚急性甲状腺炎临床情况进行分析。方法选取2015年3月—2016年5月在我院接受亚急性甲状腺炎治疗的患者126例,随机的分为对照组、观察组,各63例,对照组患者口服强的松进行治疗,观察组患者口服抗病毒药物联合小剂量强的松进行治疗,对比两组患者的临床治疗效果。结果观察组患者的发热消退时间为3 h,疼痛消退时间2.3 h,肿胀消退时间为6 h,观察组患者的发热消退、疼痛消退、肿胀消退时间少于对照组,差异具有统计学意义(P<0.05)。观察组治疗后复发率3.1%,对照组治疗后复发率为23.8%,差异有统计学意义(P<0.05)。结论使用抗病毒药物联合小剂量强的松治疗亚急性甲状腺炎能够取得良好的治疗效果。

Objective To analyze the clinical situation of treatment of subacute thyroiditis with antiviral drugs combined with low dose prednisone. Methods 126 patients with subacute thyroiditis treated in our hospital from March 2015 to May 2016 were randomly divided into control group and 63 cases in the observation group. The patients in the control group were treated with oral prednisone for observation. Group of patients with oral antiviral drugs combined with small doses of prednisone for treatment, compared the two groups of patients with clinical treatment. Results The rate of fever subsided in the observation group was 3 hours, the pain subsided time was 2.3 hours, the swelling subsided time was 6 hours, the fever of the observation group subsided, the pain subsided and the swelling subsided time was significantly less than the control group, the difference was statistically significant （P 〈0.05）. The recurrence rate was 3.1% in the observation group and 23.8% in the control group after treatment. The difference was significant （P 〈0.05）. Conclusion The use of antiviral drugs combined with small doses of prednisone in the treatment of subacute thyroiditis can achieve good therapeutic effect and is worthy of popularization in clinical practice.