肝细胞癌并肺转移的治疗研究进展

Research progress of treatment of pulmonary metastases from hepatocellular carcinoma

肝细胞癌(HCC)是世界上常见的恶性肿瘤之一,肺转移为最常见的远处转移。一旦发生肺转移,病情发展恶化迅速,常加快死亡速度。本文对肝细胞癌肺转移的治疗方法包括外科手术治疗、化疗药物治疗、放疗、微创治疗、分子靶向药物治疗和联合治疗等进行系统论述,并对上述治疗手段的优势与不足进行讨论,还就治疗方案的选择原则和个体化治疗的实施细则提出一些建设性意见,期望可为肝细胞癌併肺转移患者临床治疗方案的制订与选择提供指导,从而实现个体化治疗、以及延长患者的生存期和生活质量的目的。

Hepatocellular carcinoma（HCC） is one of the world′s most common malignant tumors and pulmonary metastasis is the most common distant metastases.In the event of pulmonary metastasis,development of deterioration is rapid,which often speed up the death.In this work,the treatment of pulmonary metastases from HCC,including surgical treatment,chemotherapy drugs, radiotherapy,minimally invasive treatment, molecular targeted drug therapy and combination therapy were discussed systematically,and the advantages and disadvantages of these treatments were discussed.The constructive suggestions on the choice of treatment regimen and the implementation details of individualized therapy were presented,and hope to give out some new insights for the development and selection of clinical treatment options in patients with pulmonary metastases from HCC in order to achieve individualized treatment,improve the patient′s survival and quality of life.