间歇声门下吸引在减少ICU患者呼吸机相关肺炎中的效果

The Effect of Intermittent Subglottic Secretion Drainage on Reducing ICU Patients With Ventilator-associated Pneumonia

目的探讨间歇声门下吸引在减少呼吸机相关肺炎(VAP)中的应用效果。方法选取我院2015年1~12月综合ICU收治的行机械通气的患者92例作为研究对象,随机分为观察组(46例)和对照组(46例)。观察组行间歇声门下吸引,对照组行常规气管导管,比较两组患者的VAP感染率、机械通气时间、住院时间。结果观察组的机械通气时间以及住院时间分别为(6.25±0.36)d、(13.65±1.65)d,对照组为(11 37±0.68)d、(19.36±2.24)d,观察组优于对照组,差异具有统计学意义(P<0.05)。观察组中有2例患者发生呼吸机相关肺炎,占4.35%;对照组有8例,占17.39%,两组比较,差异具有统计学意义(x^2=4.0390,P=0.044 5)。结论间歇声门下吸引能够明显减少VAP发生率,并缩短患者的机械通气时间,促进ICU的患者病情较快康复。

Objective To investigate the effect of intemlittent subglottic aspiration in the treatment of ventilator-associated pneumonia （ VAP ） . Methods A total of 92 patients with mechanical ventilation in our hospital from January to December 2015 were selected as the research object of ICU, they were randomly divided into observation group （ 46 cases ） and control group （ 46 cases ） . The patients in the observation group were given subglottic aspiration, while the control group received conventional endotracheal intubation, the VAP infection rate, mechanical ventilation time and hospital stay were compared between two groups. Results The mechanical ventilation time and hospitalization time in the observation group were （6.25±0.36） d, （13.65±1.65） d, the control group was （11.37±0.68） d, （19.36±2.24） d, the observation group was better than the control group, the difference was statistically significant （P 〈 0.05 ） . There were 2 cases of ventilator-associated pneumonia in the observation group, accounting for 4.35%. There were 8 cases in the control group, accounting for 17.39%, the difference between two groups was statistically significant （ X2=4.039 0, P=0.044 5 ） . Conclusion Intermittent subglottic suction can significantly reduce the incidence of VAP, and shorten the mechanical ventilation time, promote the rapid recovery of patients with ICU.