蒙药绍沙-7丸质量标准研究

Study on the criteria for the Mongolian medicine Shaosha-7 pills

目的提高蒙药绍沙-7丸的质量标准。方法用显微和薄层色谱法对绍沙-7丸中的广枣、木香、丁香、肉豆蔻、沉香、兔心进行显微鉴别,用木香烃内酯、去氢木香内酯、丁香酚及没食子酸作为对照品,对木香和丁香进行薄层色谱鉴别。结果绍沙-7丸在木香和丁香对照品斑点对应的位置具有相同颜色的清晰斑点,阴性无干扰,具有专属性,耐用性好。结论可用薄层鉴别法对绍沙-7丸木香和丁香鉴别,用显微鉴别的方法对广枣及其它成分进行鉴别,以控制其质量。

Objective The aim of this study is to improve the quality standard of Mongolian medicine Shaosha - 7 pills. Methods Microscopic identification method was used to distinguish Shaosha -7 pills. Costunolide, dehydrocostus lactone, eugenol and gal- lic acid were used as reference substances to identify Aucklandiae radix, Caryophylli flos and Choerospondiatis fructus in Shaosha - 7 pills by thin layer chromatography （TLC）. Results Choerospondiatis fructus, Aucklandiae radix, Caryophylli flos, Myristicae semen, Aquilariae lignum resinatum, and Rabbit heart were identified by microscopy. TLC result showed the clear spots in Sha- osha -7 pills appeared at the same positions corresponding to the reference substances with high specificity, and good ruggedness. Conclusion TLC can be used to identify the Aucklandiae radix and Caryophylli flos, and microscopic identification method can be used to distinguish Choerospondiatis fructus and other five components for the quality control of Shaosha -7 pills.