从“营卫不从”探讨系统性硬化症合并肺间质改变的中医病机演变

Chinese Medical Pathogenesis Evolution of Systemic Sclerosis Complicated with Pulmonary Interstitial Changes:from the View of “Disorder of Nutrient Qi and Defensive Qi”

系统性硬化症早期多归属于中医学"皮痹"范畴,后期则并发"肺痹""肺痿"等病。《素问·痹论》指出"营卫不从"是导致痹证发生的重要内因。试从营卫的生理病理特点、系统性硬化症合并肺间质改变的不同阶段的中医病机,以及调和营卫等治法在系统性硬化症合并肺间质改变治疗中的意义等方面进行相关论述,以期对临床治疗有所启示。

Systemic sclerosis（ SSc） of early stage mostly belongs to ＂skin Bi＂（ 皮痹） in Chinese medicine category. In the later stage,＂lung Bi＂（ 肺痹）,＂lung flaccidity＂and other diseases complicates. It is said in Bi Discussion（ 痹论） in Plain Questions（ 素问） that ＂disorder of nutrient Qi and defensive Qi＂is an important internal cause leading to Bi syndrome. The authors try to discuss from the aspects of physiological and pathological characteristics of nutrient Qi and defensive Qi,Chinese medical pathogenesis of SSc complicated with pulmonary interstitial changes in different stages,as well as the meaning of harmonizing nutrient Qi and defensive Qi and other methods in treating SSc complicated with pulmonary interstitial changes,to provide prompt for clinical therapy.