阻塞性睡眠呼吸暂停相关肺动脉高压

Obstructive sleep apnea associated pulmonary hypertension

随着筛查手段的不断提高,阻塞性睡眠呼吸暂停(OSA)相关肺高血压(PH)的检出率不断上升,其高发病率及所造成的诸多严重并发症使之成为一个全球广泛关注的公共问题。在其筛查诊断环节,多导睡眠检测图(PSG)、血气分析及超声心动图、右心导管检查等手段发挥了重要作用。持续正压通气(CPAP)治疗的有效性受到了广泛的认可,而对于肺动脉高压特异性药物治疗的效果尚待进一步研究。

As the improvement of scanning methods, the detection rate of obstructive sleep apnea （OSA） associated pulmonary hypertension （PH） has been significantly increased. Examination methods, such as polysomnography （PSG）, arterial blood gases analysis and echocardiograph）5 right heart catheterization （RHC） has exerted great efforts on screening and diagnosis of OSA associated PH. The effectiveness of continuous positive airway pressure （CPAP） has been widely recognized while it still needs further study whether patients with OSA and PH may benefit from specific PH therapy