结直肠锯齿状腺瘤和传统腺瘤的内镜及病理学特征比较分析

Comparative analysis of endoscopic and pathologic features between traditional tumor and serrated adenoma

目的:探讨结直肠锯齿状腺瘤和传统腺瘤的内镜及病理学特征的不同。方法:对2014年3月至2015年8月入住本院并由消化内镜中心确诊的95例结直肠锯齿状腺瘤患者与70例传统腺瘤患者的内镜、病理学特征进行分析比较。结果:95例观察组共检出隆起型息肉89枚,表面型息肉36枚,共125枚;70例对照组共检出隆起型息肉99枚,表面型14枚,共113枚;两组差异无统计学意义(P>0.05)。观察组125枚息肉主要分布于乙状结肠,其次升结肠、降结肠;对照组113枚息肉主要分布于乙状结肠,其次升结肠、降结肠、横结肠。乙状结肠组间差异具有统计学意义(P<0.05),降结肠组间比较差异也具有统计学意义(P<0.01)。组织病理学检查结果显示,结直肠锯齿状腺瘤呈锯齿状,或伴有上皮内瘤变或癌变;传统腺瘤呈绒毛状、管状或管状绒毛状,亦伴有上皮内瘤变或癌变。两组在伴低级上皮内瘤变差异具有统计学意义(P<0.01),其它异型增生无差异(P>0.05)。结论:结直肠锯齿状腺瘤与传统腺瘤相比有其独有的特征,值得临床进行进一步的研究。

Objective To investigate the endoscopic and pathologic features SA analysis and traditional adenomas are different. Methods March 2014 - August 2015 in our hospital stay by digestive endoscopy in patients with colorectal serrated adenoma center diagnosed 70 cases with conventional endoscopic adenoma, 95 cases of pathological features were analyzed and compared. Results 95 cases were detected in the observation group 89 protruded polyps, polyps surface 36, a total of 125; 70 cases in the control group were detected polyps bulge 99, the surface-type 14, a total of 113; the difference was not statistically significant, P〉 0.05. Observation group 125 polyps are mainly distributed in the sigmoid colon, followed mainly in the ascending colon, descending colon, polyps in the control group 113 is mainly distributed in the sigmoid colon, followed mainly in the ascending colon, descending colon, transverse colon. Sigmoid： difference between the groups was statistically significant, P 〈0.05; the descending colon： and the difference between groups was significant statistical significance, P 〈0.01. Histopathological examination showed that colorectal serrated serrated adenoma, or associated with neoplasia or cancer intraepithelial; tradition into villous adenoma, tubular or tubular, villous, or cancer is also associated with intraepithelial neoplasia. Significant statistical significance in the two groups with lower intraepithelial neoplasia difference, P 〈0.01; other dysplasia no difference, P〉 0.05. Conclusion Colorectal adenomas compared with traditional serrated adenoma has its unique characteristics, is worthy of further study deep.