摘要
目的对A型肉毒毒素注射治疗慢性紧张型头痛的疗效及安全性进行临床观察和研究。方法纳入慢性紧张型头痛病人共50例,分为A型肉毒毒素注射治疗组和传统药物治疗对照组,每组各25例,对两组疗效进行比较研究,并对A型肉毒毒素注射治疗的安全性进行观察。结果肉毒毒素注射治疗组较传统药物治疗对照组在治疗后1、2及3个月各项指标(头痛发作天数、发作时头痛严重程度、头痛发作持续时间、需临时口服止痛药的天数)的改善均更加显著(P<0.05)。肉毒毒素注射治疗组约72%的病例感颈部乏力,约在1周~1月内消失,无其他明显不良反应。结论 A型肉毒毒素注射治疗慢性紧张型头痛方法简便、起效快、效果显著、副反应小、药效维持时间长。
Objective To observe and study the effect and safety of BTX-A( Botulinum Toxin in Type A) injection on chronic tension headache ( CTH) . Methods 50 patients with CTH were randomly divided into 2 groups : Botulinum toxin A treatment group and tradi-tional medicine treatment group,25 cases in each group. The efficacy of the two groups were compared. The safety of BTX-A injection was observed. Results After 1 month,2 months and 3 months treatment, the indicators( headache days per month, severity of head-ache, headache duration per day,days of temporary oral analgesics) of BTX-A injection group were improved more significantly than tra-ditional medicine group. The cervical fatigue occurred in 72% of the patients treated with the injection of BTX-A,which disappeared in about 1 week tol month,and this group had no other obvious adverse reactions. Conclusion BTX-A injection for treatment of CTH is simple,fast acting,effective,less side effects and long efficacy duration.
出处
《安徽医药》
CAS
2017年第5期914-917,共4页
Anhui Medical and Pharmaceutical Journal
关键词
A型肉毒毒素
慢性紧张型头痛
疗效
安全性
Botulinum Toxin in Type A
Chronic tension headache
Effect
Security