期刊文献+

液体活检循环肿瘤细胞和循环肿瘤DNA在肝癌中的临床应用进展 被引量:8

下载PDF
导出
摘要 根据国家癌症中心发布的中国癌症统计数据,2015年全国肝癌的总发病人数46.61万人,致死人数42.21万人,肝癌的发病率在男性肿瘤位于第四而死亡率居于恶性肿瘤死因的第三位。多数原发性肝癌患者早期症状不明显,确诊时大多数患者已经达到中晚期。此外肝癌自身异质性强,
出处 《肝脏》 2017年第5期467-469,共3页 Chinese Hepatology
  • 相关文献

参考文献1

二级参考文献48

  • 1Jin‐JungChoi,Charles F.Reich,David S.Pisetsky.The role of macrophages in the in vitro generation of extracellular DNA from apoptotic and necrotic cells[J]. Immunology . 2005 (1)
  • 2Jahr S,Hentze H,Englisch S,et al.DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Research . 2001
  • 3Bettegowda C,Sausen M,Leary RJ,et al.Detection of circulating tumor DNA in early-and late-stage human malignancies. Sci Transl Med . 2014
  • 4Forshew Tim,Murtaza Muhammed,Parkinson Christine,Gale Davina,Tsui Dana W Y,Kaper Fiona,Dawson Sarah-Jane,Piskorz Anna M,Jimenez-Linan Mercedes,Bentley David,Hadfield James,May Andrew P,Caldas Carlos,Brenton James D,Rosenfeld Nitzan.Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA. Science translational medicine . 2012
  • 5Leary Rebecca J,Sausen Mark,Kinde Isaac,Papadopoulos Nickolas,Carpten John D,Craig David,O’Shaughnessy Joyce,Kinzler Kenneth W,Parmigiani Giovanni,Vogelstein Bert,Diaz Luis A,Velculescu Victor E.Detection of chromosomal alterations in the circulation of cancer patients with whole-genome sequencing. Science translational medicine . 2012
  • 6Newman AM,Bratman SV,To J,Wynne JF,Eclov NC,Modlin LA,Liu CL,Neal JW,Wakelee HA,Merritt RE,Shrager JB,Loo BW,Jr,Alizadeh AA,Diehn M.An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage. Nature Medicine . 2014
  • 7Diaz LA Jr,Bardelli A.Liquid Biopsies:Genotyping circulating tumor DNA. Journal of Clinical Oncology . 2014
  • 8Yi JM,Guzzetta AA,Bailey VJ,Downing SR,Van Neste L,Chiappinelli KB et al.Novel methylation biomarker panel for the early detection of pancreatic cancer. Clinical Cancer Research . 2013
  • 9Hideaki Kinugasa,Kazuhiro Nouso,Koji Miyahara,Yuki Morimoto,Chihiro Dohi,Koichiro Tsutsumi,Hironari Kato,Takehiro Matsubara,Hiroyuki Okada,Kazuhide Yamamoto.Detection of K‐ras gene mutation by liquid biopsy in patients with pancreatic cancer[J]. Cancer . 2015 (13)
  • 10Shinichi Yachida,Sian Jones,Ivana Bozic,Tibor Antal,Rebecca Leary,Baojin Fu,Mihoko Kamiyama,Ralph H. Hruban,James R. Eshleman,Martin A. Nowak,Victor E. Velculescu,Kenneth W. Kinzler,Bert Vogelstein,Christine A. Iacobuzio-Donahue.Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature . 2010

共引文献7

同被引文献56

引证文献8

二级引证文献65

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部