宫颈环形电切术用于宫颈癌前病变治疗的可行性研究

Research on Feasibility of Loop Electrosurgieal Excision Procedure in the Treatment of Cervical Precancerous Lesions

目的研究并探讨宫颈环形电切术用于宫颈癌前病变治疗的可行性。方法于2013年1月—2015年12月期间,方便选取该院妇科收治的100例宫颈癌前病变患者作为对象,所有患者按照单盲随机分组原则随机分为两组,每组50例,对照组实施冷刀锥切术,观察组实施宫颈环形电切术,比较两组疗效、手术情况、术后情况。结果两组总有效率、复发率比较(92%vs 96%,4%vs 2%),差异无统计学意义(P>0.05);观察组手术时间(15.56±8.76)min、术中出血量(21.17±14.42)mL等手术情况均明显优于对照组(P<0.05),且其术后创面愈合时间(1.37±0.59)d、住院时间(7.23±1.84)d、并发症发生率(2%)等术后情况也优于对照组(P<0.05)。结论在宫颈癌前病变的临床治疗中,宫颈环形电切术与冷刀锥切术治疗的效果相当,但宫颈环形电切术可有效减轻手术创伤,加快术后恢复,其预后效果相对较好。

Objective To research and discuss the feasibility of loop electrosurgieal excision procedure in the treatment of cervical precancerous lesions. Methods 100 cases of patients with cervical precancerous lesions admitted and treated in our hospital from January 2013 to December 2015 were conveniently selected as the research objects and randomly divided into two groups with 50 cases in each, the control group adopted the cold knife conization, and the observation group adopted the loop electrosurgieal excision procedure, and the curative effect, operation situation and postoperative situation were compared between the two groups. Results The differences in the total effective rate and recurrence rate between the two groups were not statistically significant（92% vs 96%,4% vs 2%）（P〈0.05）, and the operation time and intraoperative bleeding amount in the observation group were respectively（15.56±8.76） min and（21.17±14.42）mL, which were obviously better than those in the control group（P〈0.05）, after operation, the wound healing time, length of stay and incidence rate of complications were respectively（1.37±0.59）d,（7.23±1.84）d and 2%, which were better than those in the control group（P〈0.05）.Conclusion In the clinical treatment of cervical precancerous lesions, the effect of loop electrosurgieal excision procedure is similar to that of cold knife conization, but the loop electrosurgieal excision procedure can effectively relieve the operation wound and accelerate the postoperative recovery, and the prognosis effect is relatively good.