替加环素治疗肺结核并发鲍曼不动杆菌性呼吸机相关性肺炎的临床研究

Clinical experience with tigecycline in the treatment of Acinetobacter baumannii induced ventilator-associated pneumo-nia in pulmonary tuberculosis patients

分析本院2014年1月至2016年8月收治的32例肺结核患者并发鲍曼不动杆菌性呼吸机相关性肺炎而使用替加环素治疗的临床资料。4例单独用药，28例联合用药，其中26例（81．2％）患者临床治疗有效，6例（18．7％）临床治疗失败；26例治疗有效患者中23例（71．9％）获得细菌学清除。替加环素单独或与其他药物联合，可以作为肺结核患者并发鲍曼不动杆菌性呼吸机相关性肺炎的治疗选择。

To evaluate the efficacy of tigecycline for treatment of acinetobacter baumannii induced ventilator- associated pneumonia in pulmonary tuberculosis patients hospitalized in Beijing Chest Hospital from January 2014 to August 2016. 32 patients were treated with tigecycline, in which 4 patients treated with tigecycline only and 28 cases treated with tigecycline combined with other drugs. Clinical success were recorded in 26 patients （81.20%）, 23 （71.9 %） patients received bacterial eradication, and clinical failure were recorded in 6 patients （18.7 %）. Tigecy- cline used alone or in combination with other antibiotics may be selected in the treatment of pulmonary tuberculosis patients with Acinetobacter baumannii induced ventilator-associated pneumonia.