主观认知障碍的相关危险因素分析及预防

Related risk factors and prevention of subjective cognitive impairment

目的 探讨主观认知障碍（SCI）的危险因素及预防措施.方法 选取2016年3~9月在上海长征医院痴呆门诊就诊患者54例,进行简易智力状况检查量表和SCI调查问卷调查.然后采用单因素和多因素条件Logistic回归分析对数据进行处理以筛查影响因素.结果 经单因素和多因素条件Logistic回归分析,筛选出3个有意义的独立因素：年龄（OR=1.243,95%CI=1.072~1.442）、脑血管疾病史（OR=130.466,95%CI=1.688~3630.660）是SCI发生的独立危险因素;文化程度是独立保护因素（OR=0.016,95%CI=0.007~0.607）.结论 年龄与脑血管疾病史是SCI发病的危险因素,在该病防治上需主要加强危险因素的防治.文化程度是发病保护因素,因此应该倡导和鼓励老年人多思考、勤用脑.

Objective To explore the related risk factors of subjective cognitive impairment （SCI） to provide references for prevention.Methods Fifty-four patients admitted to Shanghai Changzheng Hospi-tal from March to September of 2016 were evaluated by Mini-mental State Examination （MMSE） and self-made questionnaire. Univariate and multivariate logistic regression analyses were performed on related exposure fac-tors.Results By univariate and multivariate logistic regression analyses, three meaningful independent factors were screened out. Age （OR=1.243, 95%CI=1.072-1.442） and history of cerebrovascular diseases （OR=130.466, 95%CI=1.688-3630.660） were independent risk factors of SCI, while education level （OR=0.016, 95%CI=0.007-0.607） was an independent protective factor.Conclusions Age and history of cerebrovascular diseases are risk factors of SCI. It＆#39;s necessary to enhance the prevention of the risk factors. Education level is an independent protective factor. So the aged people should be advocated and encouraged to use their brains and think more.