抑郁症与神经-免疫-内分泌网的关系以及归脾汤的治疗作用

Relations Between Depression and Nerve-Immunity-Endocrine Net and the Therapeutic Effects of Spleen-Restoring Decoction

以往对抑郁症的治疗中往往只从某单个方面进行研究,抑郁症症状多变的发病特点决定了这些治疗方法效果不佳或者会顾此失彼。抑郁症的发病机制与中医认为的人体自身的完整性及人与自然、社会环境统一性的整体观不谋而合,只有从整体进行调节才能有望进一步提高抑郁症的治疗效果,并提升抑郁症患者的生活质量。西医未来对抑郁症的治疗也将会从单一靶点、单一药物向多靶点、复方药物转变。进一步挖掘归脾汤对抑郁症的治疗机制或许能揭示抑郁症各个靶点之间的关系,甚至找到新的靶点,将更加有助于指导抗抑郁症药物的研发。

The previous research on depression is merely from single aspect. The charac, teristic of changeable symptoms of depres- sion determines that the therapeutic results are not often salisfactoD＇. The pathogenesis of depression happen to hold the same view of concept of holism between the humans, nature and social en,ironment. Only with overall regulation, the therapeutie effect on depression and the lit quality of deplssion patients can be improved. The treatment of＂ depression by western medicine will transfer from single target and single drug to muhiple targets and compound dngs. Further explm-ations of the therapeutic meeha- nism of Spleen-Restoring Decoction may reveal the relations between various targets of depression, ;and even find new targets, which will be conductive to the research and development of anti-depression drugs.