补肾化痰活血祛瘀方治疗肾虚痰瘀型多囊卵巢综合征56例

Fifty-Six Cases with Polycystic Ovarian Syndrome of Kidney Deficiency and Phlegm Stasis Pattern Treated with Kidney-Tonifying,Phlegm-Resolving and Blood-Stasis-Removing Prescription

目的:观察补肾化痰活血祛瘀方治疗肾虚痰瘀型多囊卵巢综合征的临床疗效。方法:所有患者口服肖承悰教授自拟的补肾化痰活血祛瘀方,随症加减。比较患者的临床疗效及中医证候疗效,观察患者治疗后月经恢复情况、排卵情况及妊娠情况,检测患者治疗前后血清激素水平[黄体生成素(luteinizing hormone,LH)、促卵泡生成素(follicle-stimulating hormone,FSH)、睾酮(testosterone,T)]变化情况。结果:所有患者临床疗效有效率为87.50%,中医证候有效率为94.64%;月经恢复率为57.14%,排卵率为48.21%;妊娠率为41.94%。治疗后血清T、LH、FSH及LH/FSH较治疗前下降,差异具有统计学意义(P<0.05)。结论:补肾化痰活血祛瘀方治疗肾虚痰瘀型多囊卵巢综合征具有较高的排卵率及妊娠率,且可以显著改善血中激素水平和中医证候。

Objective： To observe Ihe clinical ef＇ects of Kidney-Tonifying, Pillegm-Resolving and Blood-Stasis-Removing Prescrip- tion on polyeystic ovarian syndrome of kidney deficiency and phlegm slasis pattern. Methods： All the patients were orally given Kidney-Tonifyiug, Phlegm-Resolving an〈l Blood-Stasis-Removing Prescription fornmlated by Professor Xiao Chengcong, with mcM- ifieation aecordiwg to the symptoms. The clinical effects and effieaeies on TCM symptoms in the two groups were eonlpared. The conditions of menstruation recoveL＇, ovulation anti pregnancy alier lrealment were observed. Tl,e changes of the levels of I,H, FSH and T were detected. Resuhs ： The clinical eftct of all patients was 87.50% ; the efficacy of TCM symptoms was 94.64% ; the rectvery rate of menstruation was 57.14% ; the ovulation rate was 48.21 e ; the pregnancLs rate was 41.94-%. The levels of serum T, LH, FSH and LH/FSH declined after treatment; tile （titrence had statistical significance （ P 〈 0.05 ）. Conehlsion： Kidney-Tonityiug, Phlegm-Resolving and Bh）nd-Stasis-Removing Prescription promotes ovulation ale and pregnancy rate, im- proves the htrmme levels and TCM symptoms in patients with pol.eystie varian of kidney deficiency anti phlegm stasis pattern.