温汤胆加减治疗痰热内扰型不寐疗效观察

Clinical Observation of Modified Wendan Decoction in Treating Insomnia of Internal Distrubance Due to Phlegm Heat

目的:观察温胆汤加减治疗痰热内扰型不寐的效果及复发率情况。方法:将符合纳入标准的84例痰热内扰型不寐随机分为观察组和对照组,每组各42例,观察组服用温胆汤加减,对照组单纯应用艾司唑仑,2组均服用4周为1疗程,疗程结束后比较疗效,1个月后随访观察复发情况。结果:观察组复发率明显低于对照组,差异有统计学意义。结论:温胆汤加减治疗痰热内扰型不寐效果明显优于艾司唑仑,避免了长期服用艾司唑仑的副作用,并且复发率明显低于艾司唑仑组。值得临床推广。

Objective： To observe the effect of modified Wendan decoction in treating insomnia of internal distru- bance due to phlegm heat and the recurrence rate. Methods： 84 cases of insomnia of internal distrubance due to phlegm heat were randomly divided into observation group and control group, 42 cases in each group. The patients in the ob- servation group were treated with Wendan Decoction. The patients in the control group were treated with estazolam only. 2 patients were taking 4 weeks for a course of treatment. After treatment, the difference of clinical effect between the two groups was compared. After 1 month of treatment, the recurrence of the two groups was observed at random. Results： The relapse rate of the observation group was significantly lower than that of the control group, the difference was statistically significant. The effect of modified Wendan decoction in treating insomnia of internal distrubance due to phlegm heat was significantly better than estazolam which avoid long-term side effects of estazolam, and the recurrence rate was significantly lower than the estazolam group. Worthy of clinical promotion.