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普通肝素与低分子肝素对脓毒血症患者肝素结合蛋白浓度的影响对比 被引量:4

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摘要 目的探讨普通肝素与低分子肝素对脓毒血症患者肝素结合蛋白浓度的影响。方法选取佛山市南海区第三人民医院2015-01—2016-11间收治的30例脓毒血症患者做为研究对象。按照随机数字表将患者分为观察组15例与对照组15例,观察组患者在常规对症支持治疗基础上联合使用低分子肝素治疗,对照组患者在常规对症支持治疗基础上联合使用普通肝素治疗。比较两组患者的应用肝素治疗前后血清中肝素结合蛋白浓度水平变化情况及预后结果。结果观察组患者治疗后血清中肝素结合蛋白浓度显著低于对照组患者,差异有统计学意义(P<0.05)。观察组患者治疗后预后结果显著优于对照组患者,差异有统计学意义(P<0.05)。结论临床应用普通肝素与低分子肝素治疗脓毒血症,低分子肝素治疗对患者肝素结合蛋白浓度影响更显著,有助于降低多器官功能衰竭综合征的几率,值得广泛推广应用。
出处 《黑龙江医学》 2017年第4期341-342,共2页 Heilongjiang Medical Journal
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