穴位埋线治疗癌因性疲乏的临床观察

Effects of Acupoint Catgut Embedding on Cancer-Related Fatigue(CRF)

目的观察穴位埋线对癌因性疲乏的临床疗效。方法使用随机平行对照方法,将60例住院患者按随机数字表法简单随机分为两组。对照组30例按NCCN指南中推荐的西医常规方法进行治疗,治疗组在对照组治疗基础上,从治疗开始给予穴位埋线,1次/周,连续治疗2周,选穴:双侧足三里、关元、气海,入组后第0周、1周、2周填写相关评测量表,观察两组疲乏积分、中医症候积分、生活质量评分、不良反应,判定疗效。结果治疗组治疗后的疲乏积分、中医症候积分(气短、神疲、乏力、自汗)、KPS评分较治疗前明显改善(P<0.01),对照组治疗前后无明显改善(P>0.05)。治疗后治疗组的疲乏积分明显少于对照组(P<0.05)。治疗后的中医症候积分治疗组明显低于对照组(P<0.05)。结论穴位埋线结合西医常规治疗癌因性疲乏,临床疗效满意,优于西医常规治疗,无严重不良反应,值得推广。

Objective To investigate the treating effects of acupoint catgut embedding on cancer-related fatigue（CleF） of patients with cancer. Methods Sixty cancer patients were randomly divided into treatment group （30cases） and control group （30cases）. The control group （30cases） were treated with the conventional Western Med-icine recommended by NCCN. The treatment group were treated based on the control group and given acu-point catgut embedding, 1 times/week, for 2 weeks. Acupoints：Guanyuan, Zusanli, Qihai. Filled in the relevant asses-sment scales at the zeroth week, the end of the second week. Observed fatigue score, TCM symptom score, quality of life score, adverse reactions and determine efficacy of the two groups. Results After treatment, the fatigue integral, the TCM symptom score （shortness of breath, lassitude, weakness, sweating）, KPS score were significantly improved compared with before treatment（P〈0.01 ）. But the control group had no significant improvement after treatment（ P〉0.05 ）. After treatment, the fatigue integral and the TCM symptom score of the treatment group were significantly improved compared with the control group（ P〈0.05 ）. Conclusion Acupoint catgut embedding with routine treatment of Western Medicine could treat CRF, and was better than routine treatment of Western Medicine, alleviated cancer treatment-related symptom cluster and improve the quality of life of the patients.