摘要
目的控制清金固本胶囊的质量。方法采用薄层色谱法(TLC)对黄芩、桔梗、茯苓、防风进行鉴别,采用高效液相色谱(HPLC)法测定黄芩苷的含量。结果黄芩苷质量浓度在4.1~32.8μg/m L范围内与峰面积线性关系良好(r=0.999 9),平均回收率为95.85%,RSD为0.71%(n=6)。结论所建立的方法可为清金固本胶囊质量标准的建立提供参考。
Objective To control the quality of Qingjinguben Capsule. Methods TLC method was used to identify Scutellariae Radix, Platycodonis Radix,Poria,Saposhnikoviae Radix,Codonopsis. The content of baicalin was determined by HPLC. Results The chromato-graphic spots were clear with good separation,the chromatogram for identification by TLC was distinct and highly specific. The linear range was 4. 1-32. 8 μg/ml（r=0. 9999）,the average recovery rate was 95. 85%,RSD was 0. 71%（n=6）. Conclusion The method can provide reference for the establishment of quality standard of Qingjinguben Capsule.
出处
《中国药业》
CAS
2017年第8期12-16,共5页
China Pharmaceuticals
基金
陕西省自然科学基础研究计划项目[2012JM4053]
