中药浴足配合刮痧在糖尿病周围神经病变合并坏疽感染患者中的应用效果

Effect of foot bath with traditional Chinese medicine combined with scraping on diabetic peripheral neuropathy patients complicated with gangrene infection

目的探讨中药浴足配合刮痧在糖尿病周围神经病变合并坏疽感染患者中的应用效果。方法选取医院收治的糖尿病周围神经病变合并坏疽感染患者202例,将患者分为对照组和研究组,各101例,对照组给予常规治疗,研究组在对照组的基础上给予中药足浴配合刮痧治疗,治疗21d后,比较两组患者疗效和神经改善状况,并分析感染病原菌的分布和耐药性。结果研究组患者的显效比例及总有效率均显著高于对照组,且差异有统计学意义(P<0.05);治疗后,与组内相比,两组患者的神经状况评分、感觉功能检查评分以及神经反射评分均显著降低,研究组患者的神经状况评分、感觉功能检查评分以及神经反射评分低于对照组,差异均具有统计学意义(P<0.05);202例患者共培养出227株病原菌,以革兰阳性菌为主,117株占51.5%,主要包括表皮葡萄球菌30株、金黄色葡萄球菌22株、粪肠球菌17株,革兰阴性菌105株占46.3%,主要包括肺炎克雷伯菌26株、铜绿假单胞菌24株、大肠埃希菌21株、脆弱拟杆菌20株,真菌5株占2.2%;表皮葡萄球菌对苄卡西林、万古霉素敏感,肺炎克雷伯菌对亚胺培南、美罗培南敏感,铜绿假单胞菌对亚胺培南、美罗培南敏感。结论中药浴足配合刮痧应用于糖尿病周围神经病变合并坏疽感染患者中,可有效提升患者的总体疗效,改善患者的神经功能,值得临床推广;对于不同病原菌感染患者,给予不同的抗菌药物治疗,以提升感染患者的治疗效果。

OBJECTIVE To explore the application effect of foot bath with traditional Chinese medicine combined with scraping on diabetic peripheral neuropathy patients complicated with gangrene infection.METHODS A total of202 diabetic peripheral neuropathy patients complicated with gangrene infection who were treated in the hospital were enrolled in the study and divided into the control group and the study group,with 101 cases in each group.The control group was given conventional therapy,while the study group was given foot bath with traditional Chinese medicine combined with scraping on the basis of the therapy of the control group.The curative effect and improvement of nerve situation were observed and compared between the two groups of patients after the treatment for 21days;the distribution and drug resistance of pathogens causing the infections were analyzed.RESULTS The proportion of the patients with effective treatment and the total effective rate were significantly higher in the study group than in the control group（P〈0.05）.The scores of nerve condition,feeling function examination,and nerve reflex of the two groups of patients were significantly reduced after the treatment;the scores of nerve condition,feeling function examination,and nerve reflex of the study group were lower than those of the control group（P〈0.05）.Totally 227 strains of pathogens were cultured from the 202 patients,of which 117（51.5%）were grampositive bacteria,105（46.3%）strains of gram-negative bacteria,and 5（2.2%）strains of fungi;the Staphylococcus epidermidis（30strains）,Staphylococcus aureus（22strains）,and Enterococcus faecalis（17strains）were the predominant species of the gram-positive bacteria;the Klebsiella pneumoniae（26strains）,Pseudomonas aeruginosa（24strains）,Escherichia coli（21strains）,and Bacteroides fragilis（20strains）were dominant among the gram-negative bacteria.The S.epidermidis strains were susceptible to benzyl ticarcillin and vancomycin;the K.pneumoniae strains were susceptible to imipenem and meropenem;the P.aeruginosastrains were imipenem and meropenem.CONCLUSIONThe foot bath with traditional Chinese medicine combined with scraping,as is used for treatment of the diabetic peripheral neuropathy patients complicated with gangrene infection,can effectively raise the overall curative effect and improve the neurological function of the patients,and it is worthy to be promoted in the hospital.The patients with the infection caused by various species of pathogens should be treated with different types of antibiotics so as to raise the curative effect.