药物滥用人群传染病的疾病负担评估

Evaluation of burden of infectious diseases among drug abusers

目的了解我国吸毒人群传染性疾病的患病风险、期望寿命、治疗费用和吸毒费用,评估药物滥用人群中感染三大传染疾病的负担。方法以期望寿命年、疾病患病率、疾病治疗费用和吸毒费用为评价指标,利用马尔科夫状态转移决策模型以及成本效益模型评估吸毒人群疾病负担。结果吸毒人员平均期望寿命为13.66年;药物滥用使用第1年,丙型肝炎、艾滋病和结核病的感染率分别为50.4%、3.3%和2.7%;3年后,药物滥用人群的累计病死率为26.35%,3种传染病的感染率达到最大值,各种感染率分别为59.78%、3.71%、3.11%;20年后,药物滥用人群的累计病死率达42.95%,各传染病的感染率分别为48.28%、2.02%、2.05%;一名药物滥用人员传染性疾病每年的总费用大约为2.98万元,其中治疗费用和毒资分别是2 495.79元和27 318.8元。结论药物滥用人群传染性疾病发病风险较高,治疗疾病的成本高。

OBJECTIVE To understand the risk of getting infectious diseases,life expectancy,treatment cost,and drugs cost among drug addicts in China and estimate the burden of the three infectious diseases among the drug addicts.METHODS The life expectancy,morbidity rate,cost of treatment of diseases,and drugs cost were set as the evaluation indexes,and the burden of diseases among the drug addicts was evaluated by using Markov state transition decision model and cost-effectiveness model.RESULTS The mean life expectancy of the drug addicts was 13.66 years.The prevalence rates of hepatitis C,AIDS,and tuberculosis were respectively 50.4%,3.3%,and 2.7%in the first year of drug abuse;the prevalence rates of the three infectious diseases maximized 3years later,which were 59.78%,3.71%,and 3.11%,respectively,and the cumulative mortality rate of the drug abuse population was 26.35%.The cumulative mortality rate of the drug addicts reached up to 42.95% after 20 years,and the prevalence rates of the infectious disease were 48.28%,2.02%,and 2.05%,respectively.The total cost of one drug addict was about 29,800 yuan each year due to the infectious diseases,and the treatment cost and drugs cost were 2,495.79 yuan and 27,318.8yuan,respectively.CONCLUSIONThe drug addicts are at high risk of the infectious diseases,and the cost of treatment of the diseases is high.