急诊病房呼吸道感染患者呼吸道病毒IgM抗体检测分析

Analysis of respirtory virus IgM antibodies detection in patients with respiratory tract infection in emergency wards

目的了解该院急诊病房呼吸道感染患者呼吸道病毒感染分布情况。方法收集2014年1月至2015年12月大连医科大学附属第一医院急诊科收治的成人呼吸道感染患者5种病毒[呼吸道合胞病毒(RSV),流感病毒A型(IVA),流感病毒B型(IVB),副流感病毒1、2、3(PIV1、PIV2、PIV3)和腺病毒(ADV)]间接免疫荧光法检测结果资料,分析不同病毒的流行特征。结果384例标本中208例呼吸道病毒IgM抗体阳性,病毒感染阳性率为54.17%,以混合病毒感染和IVB感染最为常见,其病毒感染阳性率分别为26.56%和23.44%。混合病毒感染中以IVA和IVB混合感染阳性率最高,占87.25%,高于其他混合感染类型。不同性别患者之间病毒感染阳性率差异无统计学意义(P>0.05)。秋、冬两季病毒感染率较高,分别为66.06%、68.37%,高于夏、秋两季的42.31%和34.25%,差异有统计学意义(P<0.05)。青年(18~45岁)和中年(>45~60岁)病毒感染阳性率分别为64.94%和63.86%,高于老年前期(>60~75岁)、老年(>75~90岁)和长寿老人(>90岁)的48.45%、44.92%、55.56%,差异有统计学意义(P<0.05)。结论该院急诊病房呼吸道感染患者混合病毒感染和IVB感染最为常见,且病毒感染情况呈现季节和年龄特征,但不受性别因素影响。

Objective To understand the distribution situation of respiratory viral infection among adult inpatients with respiratory infection in the emergency department.Methods The detection results data of 5kinds of viruses RSV,IVA,IVB,PIV1,PIV2,PIV3 and ADV by indirect immune fluorescence assay in 384 adults patients with respiratory infection in the emergency department of our hospital from January 2014 to December 2015 were collected.The epidemic characteristics of different viruses were analyzed.Results Among 384 specimens,208cases were positive in respiratory virus IgM antibody,the viral infection positive rate was54.17%.The mixed virus infection and influenza B virus infection were most common,their viral positive rates were 26.56% and23.44% respectively,In the mixed viral infection,the positive rate of IVA + IVB mixed infection was highest,accounting for87.25%,which was higher than that of other kinds of mixed viral infection.The viral infection positive rate had no statistical difference between different genders(P>0.05).The viral infection rate was higher in autumn and winter,which were 66.06% and68.37% respectively and higher than 42.31% and 34.25%in spring and summer,the difference was statistically significant(P<0.05).The viral infection rates of youth(18-45 years old)and middle-aged(>45-60 years old)were 64.94% and 63.86% respectively,which were higher than 48.45%,44.92% and 55.56% in pre-elderly(>60-75 years old),elderly(>75-90 years old)and longevous elderly(>90years old),the differences were statistically significant(P<0.05).Conclusion The respiratory virus mixed infection and IVB infection are most common in the emergency wards,moreover the viral infection situation shows the seasonal and age characteristics,but which is not affected by sex factor.