碱热处理联合紫外光照后钛体外活性的研究

Effect of alkali-and-heat treatment combined with ultraviolet irradiation on bioactivity of titanium in vitro

目的研究碱热处理加紫外光照后钛的微观结构变化及在模拟体液中诱导羟基磷灰石沉积的能力。方法将纯钛分组处理:SLA组:喷砂酸蚀;AAH组:SLA组加碱热处理;UV组:AAH组加紫外线辐照处理。测试各组理化性质,对其进行模拟体液浸泡实验。采用扫描电镜及X射线衍射仪观察分析沉积物。结果碱热处理加紫外光照的钛具有多级孔洞的微观粗糙结构,同时引入钙、钠元素,并有最佳的表面润湿性;模拟体液浸泡后,试样表面矿化物质量最多,沉积速度最快,X射线衍射仪分析沉积物为羟基磷灰石。结论碱热处理加紫外光照后纯钛种植体具有良好的体外生物活性。

Objective To study the effect of alkali-and-heat treatment combined with ultraviolet irradiation on properties of titanium surface and the ability of inducing hydroxyapatite （HA） deposition. Methods The specimens were divided into three groups, which were treated by sandblast and acid-etch （SLA）, SLA with alkali-and-heat treatment （AAH）, AAH with ultraviolet irradiation（ UV ）. The physieochemical properties of these titanium were tested. HA deposit was examined by SEM with EDX and X-ray diffraction（XRD） af- ter simulated body fluid（SBF） immersion test. Results Rough morphology with multilevel holes was formed on titanium after acid-al- kali-heat treatment and ultraviolet irradiation. UV showed the best water contact angle, approximately 0°. Besides, calcium and sodium were induced in UV group. HA deposit was found on the specimen surfaces after SBF immersion test with the largest amount and fastest speed. Conclusions The titanium after alkali-and-heat treatment combined with uhraviolet irradiation has suitable bioactivity in vitro.