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Molecular Determinants of Human Neutralizing Antibodies Isolated from a Zika Patient

Molecular Determinants of Human Neutralizing Antibodies Isolated from a Zika Patient
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摘要 Zika virus(ZIKV),a flavivirus,is causing global concern,as accumulating evidence suggests that its infection is associated with microcephaly in newborns and neurological complications,such as Guillain-Barrésyndrome,in adults;and currently no approved countermeasure against ZIKV infections is available.This concern is further emphasized Zika virus (ZIKV), a flavivirus, is causing global concern, as accumulating evidence suggests that its infection is associated with microcephaly in newborns and neurological complications, such as Guillain-Barr6 syndrome, in adults; and currently no approved countermeasure against ZIKV infections is available. This concern is further emphasized by recent parallel studies by Dr. Michael Diamond from Washington University School of Medicine and Dr. George Fu Gao frorn the Institute of Microbiology, Chinese Academy of Sciences (IMCAS) that infection with ZIKV in mice could result in acute and chronic testicular damage and eventually lead to infertility. In accordance with this observation in mice, sexual transmission of ZIKV have been documented clinically,
作者 YAN Jinghua
出处 《Bulletin of the Chinese Academy of Sciences》 2017年第1期48-49,共2页 中国科学院院刊(英文版)
基金 supported by the State Key Program for Research and Development of China the special project of Zika outbreak under the program for urgent epidemic prevention control sponsored by the Ministry of Science and Technology Dr.WANG Qihui is supported by the Young Elite Scientist Sponsorship Program of the China Association for Science and Technology Dr.George Fu Gao is a leading principal investigator of innovative research group sponsored by the National Science Foundation of China(NSFC)
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