肠道准备对全膀胱切除尿流改道术后并发症影响的系统分析

A system analysis of effect of bowel preparation on postoperative complications of patients undergoing radical cystectomy with ileal conduit diversion

目的通过Meta分析对比术前肠道准备对全膀胱切除尿流改道术后并发症的影响。方法检索维普中文科技期刊数据库、中国知网数据库、中国万方数据库、中国生物医学数据库、Pubmed、Medline、Embase从建库至2016年4月关于有无肠道准备的随机对照和队列研究,比较肠道准备和无肠道准备在全膀胱切除尿流改道术后伤口、肠道功能、感染等并发症的差异。结果共纳入3篇RCT文献,4篇队列研究文献,共656例患者。在伤口感染、伤口裂开、筋膜裂开、肠梗阻、吻合口瘘、肠瘘、尿漏、死亡观察指标中,均无统计学差异。结论术前肠道准备没有降低全膀胱切除尿流改道术后并发症的发生。

Objective To compare the impact of bowel preparation on postoperative complications of patients undergoing radical cystectomy（RC） with ileal conduit diversion （ICD） by recta-analysis. Methods All literature were collected from VIP, CNKI, WanFang Data, CB- Mdisc,Pubmed, Medline, Embase dated from inception to April 2016. Then literature were grouped into mechanical bowel preparation and nonmechanieal bowel preparation, whose differences in the wound, intestinal function, infection and other complications were compared. Results Three RCTs,four cohort studies and 656 cases were taken into account. No statistical difference was observed in the wound infection,wound dehiscence, fascia dehiscence,intestinal obstruction,anastomosis fistula, intestinal fistula, urinary leakage, death of indicators between the two groups. Conclusion Preoperative mechanical bowel preparation did not reduce the occurrence of postoperative complications of the patients with RC undergoing ICD.