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SRC-3和PAX2在乳腺浸润癌组织中的表达 被引量:1

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摘要 目的:通过对女性乳腺癌癌旁正常组织、乳腺浸润癌中PAX2与SRC-3相关蛋白分析是否相关并且有无临床意义。方法:通过免疫组化SP法研究乳腺癌及正常组织中SRC-3,PAX2是否有表达。结果:SRC-3在乳腺浸润癌中的阳性表达率为78.89%,在正常乳腺组织的阳性表达率为21.11%,差异具有统计学意义(P<0.05)。PAX2在乳腺浸润癌组织的阳性表达率为30.00%,在癌旁正常组织的阳性表达率为94.44%,其在癌旁正常组织的表达明显高于乳腺浸润癌组织中,差异具有统计学意义(P<0.05)。结论:SRC-3与PAX2可能是乳腺浸润癌的不良预后因素;二者共同参与了乳腺癌细胞增殖、侵袭及转移。
出处 《黑龙江医药科学》 2017年第1期48-49,52,共3页 Heilongjiang Medicine and Pharmacy
基金 黑龙江省青年基金批准号 编号:QC2013C013 佳木斯大学青年基金 编号:sq2013-013
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