用隔附子饼灸法对脾肾阳虚型溃疡性结肠炎患者进行治疗的效果探析

Observation on the Intervention Effect of Separated Cassia Moxibustion on UC Patients with Spleen Kidney Yang Deficiency

目的:探讨用隔附子饼灸法对脾肾阳虚型溃疡性结肠炎患者进行治疗的临床效果。方法:对2015年6月至2016年6月期间甘肃省中医院肛肠科收治的48例脾肾阳虚型溃疡性结肠炎患者的临床资料进行回顾性研究。随机将这48例患者分为柳氮磺吡啶组和隔附子饼灸组,每组各有24例患者。对柳氮磺吡啶组患者使用柳氮磺吡啶片进行治疗,对隔附子饼灸组患者使用隔附子饼灸法进行治疗,然后比较两组患者的中医疗效、西医疗效、Baron分级及其发生不良反应的情况。结果:1)在中医疗效方面,隔附子饼灸组患者治疗的总有效率高于柳氮磺吡啶组患者,差异有统计学意义(P<0.05)。2)治疗后,两组患者的Baron分级均优于治疗前,差异有统计学意义(P<0.05),但组间相比差异无统计学意义(P>0.05)。3)在西医疗效方面,两组患者治疗的总有效率相比差异无统计学意义(P>0.05)。隔附子饼灸组患者治疗的显效率高于柳氮磺吡啶组患者,差异有统计学意义(P<0.05)。4)隔附子饼灸组患者不良反应的发生率低于柳氮磺吡啶组患者,差异有统计学意义(P<0.05)。结论:用隔附子饼灸法对脾肾阳虚型溃疡性结肠炎患者进行治疗的临床效果显著,能有效地改善其临床症状,且治疗的安全性较高。

Objective To observe the changes of before and after treatment of spleen-kidney-yang-deficiency and ulcerative colitis patients treated with Cassia Separatae moxibustion,and compare the therapeutic effect of sulfasalazine tablets,qualitatively and quantitatively determine the difference of curative effect of two intervention methods,To provide clinical reference for UC treatment.Methods 48 patients were randomly divided into treatment group and control group according to the order of treatment,24 cases in each group.The treatment group was treated with Corydalis moxibustion,while the control group was treated with western medicine alone.Before and after treatment,the two groups were graded according to the classification criteria of TCM symptoms and Baron classification.Results The treatment of ulcerative colitis with spleen-kidney-yang deficiency was better than that treated with sulfasalazine.The treatment group was cured in 3 cases,markedly effective in 18 cases,effective in 3 cases and ineffective in 0 cases.The effective rate was 91.67%（P0.05）.In the control group,1 case was cured,12 cases were markedly effective,9 cases were effective and 2 cases were ineffective.The total effective rate was 87.5% and 83.33% respectively.There was no statistically significant difference between the two groups（P0.05）.Conclusion Acanthopanax moxibustion is better than traditional Chinese medicine in improving TCM symptoms,and it is better than western medicine.