拉贝洛尔治疗妊娠高血压的临床疗效及对分娩结局的影响

Clinical Effect of Labetalol in the Treatment of Pregnancy Induced Hypertension and the Influence on Delivery Outcomes

目的探讨拉贝洛尔治疗妊娠高血压患者的临床疗效及对分娩结局的影响。方法选取我院2015年1月至2015年12月收治的200例妊娠高血压患者,根据不同的治疗方案将其分为对照组和观察组各100例。观察组采用拉贝洛尔治疗,对照组采取常规治疗方法。治疗后,比较两组患者的收缩压、舒张压和分娩结局。结果治疗后,观察组的舒张压和收缩压均显著低于对照组,差异有统计学意义(P<0.05)。观察组的早产、窒息、宫内窘迫和胎盘早剥发生率均显著低于对照组,差异有统计学意义(P<0.05)。结论采用拉贝洛尔治疗妊娠高血压患者,可有效降低患者的血压以及早产、窒息、宫内窘迫和胎盘早剥发生率,值得临床推广应用。

Objective To explore the clinical effect of labetalol in the treatment of patients with pregnancy induced hypertension and the influence on delivery outcomes. Methods 200 cases of patients with pregnancy induced hypertension admitted to our hospital from January 2015 to December 2015 were selected and divided into control group and observation group according to different treatment, with 100 cases in each group. The observation group was treated with labetalol, while the control group received conventional treatment. After treatment, the systolic pressure, diastolic pressure and delivery outcomes were compared between two groups. Results After treatment, the diastolic pressure and systolic pressure of observation group were significantly lower than those of control group, with statistical differences （P〈0.05）. The incidences of premature birth, asphyxia, intrauterine distress and placental abruption of observation group were significantly lower than those of control group, with statistical differences （P〈0.05）. Conclusions Labetalol in the treatment of patients with pregnancy induced hypertension can effectively reduce blood pressure and incidences of premature birth, asphyxia, intrauterine distress and placental abruption, which is worthy of clinical promotion and application.