胃肠道间质瘤的临床病理特征及危险度分级的影响因素

Clinicopathological features of gastrointestinal stromal tumors and influence factors of risk stratification

目的:分析胃肠道间质瘤(gastrointestinal stromal tumors,GISTs)的临床病理特点,探讨GISTs的临床病理因素与危险度分级的相关性。方法:回顾性分析77例手术切除的原发性GISTs患者的临床病理资料,检测GISTs的临床病理因素与危险度分级的相关性。结果:肿瘤是否囊性变、有无坏死、是否合并其他肿瘤是对GISTs危险度分级有显著影响的变量(P<0.05)。结论:肿瘤是否囊性变及有无坏死可以作为判断GISTs危险度分级的重要参考指标。

Objective： To analyze the clinicopathological features of gastrointestinal stromal tumors （GISTs）, and to explore the correlation between clinical pathologic factors and risk stratification of GISTs. Methods： The clinicopathological data of 77 cases of primary GISTs were analyzed retrospectively. The correlation between clinical pathologic factors and risk stratification of GISTs were detected by statistical method. Results： Whether the tumor is cystic degeneration, with or without necrosis, whether the merger of other tumors was GISTs risk stratification significantly affected variables （P〈0.05）. Conclusion： Whether cystic degeneration and necrosis can be used as an important reference index to judge the risk stratification of GISTs.