比较小卒中的溶栓和双抗治疗

Comparasion of intravenous thrombolysis and dual antiplated therapy in minor stroke

目的:探讨小卒中的治疗方案。方法:回顾性总结我院36例小卒中(发病均在4.5小时以内)的诊疗资料,治疗组18例给予尿激酶静脉溶栓,对照组18例首剂给予阿司匹林300mg+氯吡格雷300mg,之后两组均给予阿司匹林100mg+氯吡格雷75mg治疗3周,评估发病24小时、1周、3月后卒中恢复或复发情况,结合文献资料进行分析。结果:发病24小时后:治疗组总有效率为88.88%,对照组为72.22%,两组数据比较差异显著(P<0.05);发病1周后:治疗组总有效率为83.33%,对照组为61.11%,两组数据比较差异显著(P<0.05);3月后预后评价:治疗组疗效良好为77.78%,对照组为55.56%,两组数据比较差异显著(P<0.05)。结论:对于小卒中患者,积极的静脉溶栓可降低患者致残率,改善患者的预后。

Objective：To investigate the treatment for acute ischemic minor stroke. Methods：Diagnosis and treatment date of 36 patients with acute minor stroke in our hospital were retrospectively studied. 18 patients were treated with UK, 18 patients were treated with Asprin and Clopidogrel. Recuperation and palindromia of acute ischemic minor stroke after 24h, lweek, 3months were assessmented. Results： After 24h： the treatment group： the effective percentage was 88. 89%. The control group： the effective percentage was 72. 22%. The date of the two groups were significantly different. After 1 week., the treat- ment group：the effective percentage was 83. 33%. The control group： the effective percentage was 61. 11%. The date of the two groups were significantly different. After 3 months： the treatment group： the good curative effect was 77. 78%. The con- trol group： the good curative effect was 55.56%. The date of the two groups were significantly different. Conclusion.. For pa- tients with acute minor stroke, intravenous thrombolysis can reduce disability rate and improve prognosis.