摘要
EB病毒(Epstein-Barr virus,EBV)是胃癌发生的生物学病因之一,EBV相关性胃癌(EBV associated gastric carcinoma,EBVaGC)具有独特的临床病理学特征,其预后相对较好,因此EBV导致胃癌的机制研究也备受关注。近年来,随着分子生物学技术的发展,EBVaGC组织中EBV病毒基因表达的研究逐渐增多,为EBVaGC的诊断、治疗和预防提供了一定的理论依据。本文就EBVaGC组织中EBV病毒基因的表达进行综述。
Epstein-Barr virus (EBV) is a biological factor associated with gastric carcinoma. The prognosis of EBV-associated gastric carcinoma (EBVaGC) is good because of its distinct clinicopathological features. The pathogenesis mechanism of EBVaGC is extensively in- vestigated at present. The development of molecular techniques has stimulated the research on the expression of EBV genes in EB- VaGC, thereby providing a theoretical foundation on the diagnosis, therapy, and prevention of EBVaGC. This article reviewed present research advances in EBV genes in EBVaGC.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2017年第9期444-448,共5页
Chinese Journal of Clinical Oncology
基金
国家自然科学基金项目(编号:81572062)资助~~