一种适合工业化制备盐酸美金刚的方法

One Suitable Industrial Method for Preparing Memantine Hydrochloride

提供一种盐酸美金刚的制备方法,以1,3-二甲基金刚烷为起始物料,经Ritter反应、碱性水解、盐酸化成盐和用水重结晶得到盐酸美金刚原料药。

Providing a process for preparing memantine hydrochloride, 1,3-dimethyl adamantane as a starting material, by the Ritter reaction, basic hydrolysis, salt and recrystaltized from water to obtain memantine hydrochloride APIs.