急性缺血性卒中再灌注治疗后血管再闭塞

Reocclusion after reperfusion therapy in patients with acute ischemic stroke

急性缺血性卒中是最常见的卒中类型，在发病4．5h内进行静脉溶栓仍是目前最有效的治疗方法。其他再灌注治疗，如血管内血栓切除术也显示出其安全性和有效性。然而，部分接受再灌注治疗的患者会出现血管再闭塞，且与转归不良相关。文章对再灌注后血管再闭塞的发生机制和可能防治措施进行了综述。

Acute ischernic stroke is the most common type of stroke. At present, intravenous thrombolysis within 4. 5 h after onset is still the most effective treatment method. Other reperfusion therapies such as endovascular thrombectomy are also shown to be safe and effective. However, some patients will have reocclusion and it is associated with poor outcome. This article reviews the mechanism and possible measures of prevention and treatment for restenosis after thrombolysis.