不同溶栓方法治疗心源性脑栓塞的对比分析

Comparative Analysis of Different Thrombolytic Therapy in Patients With Cardiogenic Cerebral Embolism

目的探讨对比不同溶栓方法治疗心源性脑栓塞的临床效果。方法将我院收治的81例心源性脑栓塞患者根据溶栓方法分组,定义接受静脉溶栓治疗的40例患者作为对照组,另外采用动脉溶栓治疗的41例患者作为观察组,观察对比两组患者的溶栓效果。结果两组总有效率对比差异不具有统计学意义(P>0.05);治疗后观察组血管再通率、NIHSS评分以及GCS评分均明显优于对照组(P<0.05)。结论动脉溶栓治疗心源性脑栓塞效果与静脉溶栓效果相当,但是动脉溶栓治疗可改善患者神经功能缺损以及提高血管再通率。

Objective To investigate the clinical effect of different methods of thrombolytic therapy for cardiogenie cerebral embolism, Methods In our hospital, 81 cases of patients with cardiogenic cerebral embolism thrombolysis according to the grouping method, defined for intravenous thrombolytic therapy in 40 patients as control group, 41 cases in the arterial thrombolytic therapy were chosen as the observation group. The thrombolytic effect of two groups were observed. Results The total efficiency of the two groups were compared the difference was not statistically significant （P〉0.05）, After treatment, in observation group, the recanalization rate, NIFISS score and GCS score were slgnifieantly better than the control group （P〈0,05）. Conclusion The effect of intra-arterial thrombolytic therapy for cardiogenic cerebral embolism is comparable to that of intravenous thrombolysis, However, arterial thrombolytic therapy can improve neurological deficits and improve the rate of recanalization.