针刺配合穴位注射对脑梗死恢复期患者高同型半胱氨酸血症的影响

Effect of Acupuncture plus Acupoint Injection on the Hyperhomocystinemia in the Convalescent Stage of Cerebral Infarction patients

目的观察针刺配合穴位注射对脑梗死恢复期患者高同型半胱氨酸血症的影响。方法将120例脑梗死恢复期伴高同型半胱氨酸血症的患者随机分为A组、B组和C组,每组40例。3组患者均接受常规西医治疗及康复治疗,A组在此基础上采用醒脑开窍法针刺治疗,B组采用注射用腺苷钴胺穴位注射治疗,C组采用醒脑开窍法针刺配合穴位注射治疗。观察3组治疗前后血浆同型半胱氨酸(HCY)水平、Barthel指数(BI)评分和美国国立卫生研究院卒中量表(NIHSS)评分的变化情况。结果 3组治疗后各项指标(HCY水平、BI评分及NHISS评分)与同组治疗前比较,差异均具有统计学意义(P<0.01)。C组治疗后各项指标与A组和B组比较,差异均具有统计学意义(P<0.05,P<0.01)。B组治疗后HCY水平与A组比较,差异具有统计学意义(P<0.05)。结论针刺配合穴位注射能显著改善脑梗死恢复期伴高同型半胱氨酸血症患者的HCY水平,提高患者日常生活活动能力及神经功能。

Objective To observe the effect of acupuncture plus acupoint injection on the hyperhomocystinemia in the convalescent stage of cerebral infarction patients.Method A total of 120 patients in the convalescent stage of cerebral infarction with hyperhomocystinemia were randomized into group A, group B, and group C, 40 cases in each group. The three groups were intervened by conventional western medicine treatment and rehabilitation therapy, the group A was byXing Nao Kai Qiao acupuncture treatment in addition, the group B was by acupoint injection with cobamamide for injection and the group C was byXing Nao Kai Qiao acupuncture plus acupoint injection treatment. The change of the plasma homocysteine （HCY） level, the Barthel Index （BI） score and National Institutes of Health Stroke Scale （NIHSS） score were observed before and after treatment.ResultEach index（the HCY level, BI score and NIHSS score） in the three groups was significantly changed after treatment（P〈0.01）. Each index in the group C was significantly different from that in the group A and group B after treatment（P〈0.05,P〈0.01）. The HCY level of the group B after the treatment was significantly different from that of the group A.Conclusion Acupuncture plus acupoint injection can significantly change the HCY level of the convalescent stage of cerebral infarction patients with hyperhomocystinemia, improve the activity of daily living and nerve function.