万菲乐治疗勃起功能障碍的临床疗效和安全性研究(附100例报告)

Efficacy and safety of Wanfeile in the treatment of erectile dysfunction:Report of 100 cases and review of the literature

目的:探讨万菲乐治疗男性勃起功能障碍的临床疗效观察及安全性。方法:100例ED患者口服100 mg万菲乐3日1次,3个月为1个疗程,比较治疗前后国际勃起功能指数调查表5个简化问题(IIEF-5)的评分,评估临床总有效率以及观察不良反应。结果:万菲乐治疗ED患者的临床总有效率达95.6%,不同程度组的ED患者IIEF评分均较治疗前有统计学差异(P<0.05),发生药物不良反应共5例(5.50%),均是一过性的,程度轻微。结论:万菲乐治疗男性勃起功能障碍是安全有效的。

Objective： To investigate the clinical effect and safety of Wanfeile in the treatment of erectile dysfunction （ ED ）. Methods： Totally 100 ED patients received oral Wanfeile at 100 mg, once every 3 days, for a course of 3 months. We compared the IIEF-5 scores of the patients before and after medication and among the patients with different degrees of ED. We evaluated the total clinical effectiveness of Wanfeile and analyzed adverse reactions. Results： The total effectiveness rate of Wanfeile was 95.6%. All the patients showed significant improvement in the IIEF-5 scores after treatment as compared with the baseline （ P 〈 0.05 ）. Adverse reactions were observed in 5 cases （5.50%）, all mild and transient. Conclusion ： Wanfeile is safe and efficacious for the treatment of ED.