呼出气一氧化氮测定诊断小儿咳嗽变异性哮喘的意义评析

Analysis of the Significance of Exhaled Nitric Oxide in the Diagnosis of Pediatric Cough Variant Asthma

目的探讨呼出气一氧化氮用于小儿咳嗽变异性哮喘的临床诊断意义。方法选取2014年7月—2016年7月在我院进行治疗的咳嗽变异性哮喘患儿65例作为观察组,同时选择同期在我院进行健康检查的正常儿童65例作为对照组,对两组儿童进行呼出气一氧化氮测定,根据测定结果评析呼出气一氧化氮在小儿咳嗽变异性哮喘诊断中的临床意义。结果观察组患儿的呼出气一氧化氮浓度高于对照组儿童,差异具有统计学意义(P<0.05)。结论小儿咳嗽变异性哮喘的呼出气一氧化氮浓度高于正常值,可将呼出气一氧化氮浓度作为诊断小儿咳嗽变异性哮喘的有效指标。

Objective To investigate the clinical significance of exhaled nitric oxide in children with cough variant asthma. Methods 65 cases of patients with cough variant asthma who were treated in our hospital from July 2014 to July 2016 were selected as the observation group. 65 cases of normal children were selected as the control group in the same period. The effects of exhaled nitric oxide on the diagnosis of cough variant asthma in children were evaluated according to the results of the study. Results The exhaled nitric oxide concentration in the observation group was significantly higher than that in the control group, the difference was statistically significant （P 〈 0.05）. Conclusion The exhaled nitric oxide concentration of children with cough variant asthma is significantly higher than the normal value, and the exhaled nitric oxide concentration can be used as an effective index for the diagnosis of cough variant asthma in children.