献血者血液中抗-HCV、HCV-RNA与ALT检测结果探讨

Study on Test Results of Anti-HCV, HCV-RNA and ALT in Blood of Blood Donors

目的研究在患者血液中存在病毒抗体(抗-HCV)、丙氨酸转氨酶(ALT)、丙肝病毒核糖核酸(HCV-RNA)等的情况。方法方便选取该院血液检验科自2015年11月—2016年11月期间接收的160例献血者血液样本,采取随机数字表法的形式随机分为两组,即为参照组(n=80)与实验组(n=80),将实行ELISA检测的患者作为参照组,将实行NAT检测的患者作为实验组,分析对比两组患者HCV-RNA、抗-HCV以及ALT检测结果。结果实验组献血者合格人数为71例,不合格人数为9例,总合格率为88.75%,参照组合格人数29例,不合格人数51例,总合格率36.25%,组间数据差异有统计学意义(P<0.05)。结论在检测献血者血液中HCV-RNA、抗-HCV以及ALT时ELISA检测与NAT检测均具备一定效果,但是NAT检测能够有效弥补ELISA检测的风险,需要进一步深入分析血液样本传染病检测措施。

Objective To research the anti-HCV, HCV-RNA and ALT in blood in blood donors. Methods 160 cases of blood samples admitted and treated in our hospital from November 2015 to November 2016 were convenient selected and randomly divided into two groups with 80 cases in each, the control group were given the ELISA test, while the experimental group were given the NAT test, and the anti-HCV, HCV-RNA and ALT test results were compared between the two groups. Results There were 71 qualified cases and 9 unqualified cases and the total qualified rate was 88.75% in the experimental group, and in the control group, 29 cases were qualified and 51 cases were unqualified, and the total qualified rate was 36.25%, and the differences between groups were obvious with statistical significance, P <0.05. Conclusion Both ELISA test and NAT test in testing the anti-HCV, HCV-RNA and ALT in blood can produce a certain effect, but the NAT test can effectively make up for the test risk of ELISA, and we need to further analyze the test measures of blood samples infectious diseases.