脑电图和经颅多普勒对儿童偏头痛的临床价值研究

Research on Clinical Value of Electroencephalogram and Transcranial Doppler Sonography on the Migraine in Children

目的探讨脑电图和经颅多普勒对儿童偏头痛的临床价值。方法方便选取2015年8月—2016年8月来该院治疗偏头痛的患儿52例,为实验组,对患者发作期、发作间歇期进行EEG(脑电图)、TCD(多普勒超声)检查。并选取同时期来该院进行健康体检的患儿52例,为对照组。将两组情况进行比较分析。结果 52例患儿中,经TCD检测显示脑血流动力学正常的有8例(15.38%),脑血流动力学出现异常者44例(84.62%),其中血流速度减慢患儿有13例,血流速度增高患儿有12例,双侧血流速度不对称有14例,血流不稳定患儿有5例。52例偏头痛患儿中,描记脑电图表现出现异常的患儿有24例(46.15%),其中轻度异常10例,中度异常7例,重度异常3例,癎样放电4例,正常范围28例(53.75%)。在两组检查中,经TCD检查与EEG检查共同表现异常的有11例。经过TCD检查EEG检查的患者结果与临床病理检查符合率分别为94%和93%,差异无统计学意义(P>0.05)。结论对偏头痛患儿行脑电图和经颅多普勒检查,诊断准确性较高,对于后续治疗、用药也有较大的借鉴价值,临床价值较高,值得在临床上推广应用。

Objective To discuss the clinical value of electroencephalogram and transcranial Doppler sonography on the migraine in children. Methods Conclusion selection 52 cases of children with migraine treated in our hospital from August2015 to August 2016 were selected and the patients were examined by the EEG and TCD during the onset period and gointoaction the intermittment period, at the same time, 52 cases of healthy physical examination children in our hospital at the same period were selected as the control group, and the situations were compared and analyzed between the two groups.Results Of the 52 cases of children, the TCD test showed that there were 8 cases whose cerebral hemodynamics was normal,accounting for 15.38%, 44 cases whose cerebral hemodynamics was abnormal, accounting for 84.62%, 13 cases whose blood flow velocity slowed down, 12 cases whose blood flow velocity increased and 14 cases whose bilateral blood flow rate was asymmetric, and 5 cases whose blood flow was not steady, of 52 cases of children with migraine, the electroencephalogram showed that there were 24 cases were abnormal, accounting for 46.15%, including 10 mild abnormal cases, 7 cases moderate abnormal cases and 3 severe abnormal cases, 4 cases with epileptiform discharge, and 28 cases were in the normal range, accounting for 53.75%, and the TCD examination and EEG examination showed there were 11 abnormal cases, and the coincidence rate of TCD examination and EEG examination and clinical pathology examination was respectively 94%and 93%, and the difference was not obvious, without statistical significance(P>0.05). Conclusion The accuracy of electroencephalogram and transcranial Doppler sonography on the migraine in children is higher, which is of great reference value to the subsequent treatment and medication with higher clinical value, and it is worth clinical promotion and application.