毛韧革菌中的韧革菌素类似物（英文）

Vibralactone derivatives from Stereum hirsutum FP-91666

从毛韧革菌(Stereum hirsutum FP-91666)的YMG发酵液中分离得到1个新的韧革菌素类似物——韧革菌素R(1)以及3个已知的类似物——韧革菌素(2-4)。利用硅胶色谱、凝胶色谱等方法,结合半制备型HPLC对该菌次生代谢产物进行研究得到这些化合物,并通过核磁共振(包括1D-NMR、2D-NMR)、高分辨质谱实验(HR-ESI-MS)、紫外光谱等波谱学方法鉴定其结构。

In order to study the secondary metabolites of Stereum hirsutum FP-91666, four vibralactone derivatives were isolated from YMG fermentation broth products of this strain —— one new vibralactone derivative, vibralactone R（1）, together with three known vibralactones（2-4）—— by the methods of silica gel chromatography, gel chromatography, and semi-preparative HPLC and so on. The new structure was elucidated by spectroscopic data including HR-ESI-MS experiments, 1D and 2D NMR.