自拟降脂汤治疗高脂血症(痰湿血瘀型)的临床效果

The clinical effect of homemade lipid-lowering decoction in treatment of hyperlipidemia (wet phlegm and blood stasis type)

目的 :观察自拟降脂汤治疗痰湿血瘀型高脂血症的临床效果。方法 :收集2014年10月—2015年9月收治的痰湿血瘀型高脂血症患者93例,随机分为自拟降脂汤组31例,给予自拟降脂汤30 ml每天2次;六君子汤组31例,给予六君子汤30 ml每天2次;对照组31例,给予标准饮食调节和体育锻炼。分别检测三组治疗总有效率及治疗前、治疗后3、6、9个月时的总胆固醇(TG)、三酰甘油(TC)、高/低密度脂蛋白胆固醇(H/LDL-C)水平。结果 :对照组总有效率为19.4%(6/31),六君子汤组为71.2%(23/31),自拟降脂汤组为87.1%(27/31)。治疗9个月后,六君子汤组TG、TC、HDL-C水平与对照组相比差异均有统计学意义(P<0.05);自拟降脂汤组TG、TC、HDL-C、LDL-C水平与对照组及六君子汤组相比,差异均有统计学意义(P<0.05)。结论 :自拟降脂汤治疗痰湿血瘀型高脂血症降脂效果明显,可有效改善其血脂水平,是一种治疗痰湿血瘀型高脂血症的安全、有效的中药方剂。

Objective：To observe the clinical effect of homemade lipid-lowering decoction in treatment of hyperlipidemia （wet phlegm and blood stasis type）. Methods ： Ninety three patients with hyperlipidemia （wet phlegm and blood stasis type） from October 2014 to September 2015 were collected and randomly divided into three groups with 31 in each. The patients in lipid-lowering decoction group received lipid-lowering decoction 30 ml each time, 2 times a day. The patients in liujunzi decoction group received liujunzi decoction 30 ml each time, 2 times a day. The patients in control group received standard diet and exercise. The clinical curative effect was calculated. The levels of triglyceride（TC）, total cholesterol（TG）, and high/low density lipoprotein cholesterol, H/LDL-C were observed before and after treatment for 3, 6 and 9 months. Results： The total effective rate was 19.4%（6/31）in control group, 71.2% （23/31）in liujunzi decoction group and 87.1%（27/31）in lipid-lowering decoction group. The levels of TG, TC and HDL-C in liujunzi decoction group after treatment for 9 months were significant differences compared with control group （P（0.05）. The levels of TG, TC, HDL-C and LDL-C in lipid-lowering decoction group after treatment for 9 months were significant differences compared with liujunzi decoction group and control group （P（0.05）. Conclusion ： Homemade lipid-lowering decoction has obvious effect in treatment of hyperlipidemia （wet phlegm and blood stasis type）. It can effectively improve the blood lipid levels of patients and is a safe and effective prescription of traditional Chinese medicine in treatment of hyperlipidemia（wet phlegm and blood stasis type）.